Maternal Cytomegalovirus Antibodies during Early and Late (Persistent) Phases after Primary Cytomegalovirus Infection during Pregnancy: An Observational Study

Background: We analyzed both early and late (persistent) phases of each cytomegalovirus (CMV) antibody in mothers with primary CMV infection during pregnancy subsequent congenital for a long period from to after delivery using our stored serum samples. Methods: used samples obtained immunoglobulin (Ig) G seroconversion infant infection. antibodies, including IgG titer, IgM avidity, were assessed the Denka assay, assay Ver.1 Ver.2, Enzygnost avidity respectively. dynamics correlations antibody, calculating Pearson’s correlation coefficients (R2). Results: 67 12 included participants between 2013 2018. increased until 61 weeks did not change significantly after. decreased 52 that assays. 64 In IgM, strong positive was found (R2 = 0.9326) two different Serum results phase (after 60 weeks) subsumed into area high low which probably equivalent persistent IgM. Conclusions: antibodies